Clonidine, sold under the brand name Catapres among others, is an α2-adrenergic agonist[7] medication used to treat high blood pressure, attention deficit hyperactivity disorder, drug withdrawal (alcohol, opioids, or nicotine), [menopausal flushing](https://anagora.org/menopausal-flushing), diarrhea, spasticity and certain pain conditions.